What is sertraline?

• Sertraline is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive symptoms.

• Sertraline is used to treat depression, obsessive-compulsive disorder, panic disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

• Sertraline may also be used for purposes other than those listed in this medication guide.

What should I discuss with my doctor before taking sertraline?

• You may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication, especially if you are under 18 years old. Talk with your doctor about this risk. While you are taking sertraline you will need to be monitored for worsening symptoms of depression and/ or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. In addition to you watching for changes in your own symptoms, your family or other caregivers should be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

• Do not use sertraline if you are using pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with sertraline. You must wait at least 14 days after stopping an MAO inhibitor before you can take sertraline.

• Before taking sertraline, tell your doctor if you have:

  • liver or kidney disease;

  • seizures or epilepsy;

  • bipolar disorder (manic depression); or

  • a history of drug abuse or suicidal thoughts.

• If you have any of these conditions, you may not be able to use sertraline, or you may need a dosage adjustment or special tests during treatment.

• FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether sertraline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

General Information Zoloft

Zoloft (sertraline) belongs to the SSRI group of antidepressants. As well as depression, it is also prescribed to treat panic and anxiety disorders, and OCD (obsessive compulsive disorder).

Zoloft Side-effects

The side-effects of Zoloft include dry mouth, drowsiness, sweating, blurred vision and constipation, although most of these should diminish over time. You may experience some nausea and dizziness when you first start taking it, however these usually dissappear in a week or two.

A lowered sex drive is also a common side effect of this, as with most antidepressants.

A small proportion of people have found that coming off Zoloft can have flu-like sypmtoms such as headaches, runny nose, congestion and coughing.

If you experience any unusual symptoms or are concerned about side effects in anyway, it is important that you discuss this with your doctor or consult a pharmacist for advice. Usually these will not be anything to worry about, but best to be sure.

Zoloft Dosage

For depression and obsessive compulsive disorder the usual starting dose for Zoloft is one 50mg tablet each day. Your doctor will increase this as appropriate. The maximum recommended dose of Zoloft is 200mg/day.

Zoloft Warning

Zoloft should not be taken while taking any other antidepressant, particularly an MAOI.

Don't stop taking Zoloft or change the dose without checking with your doctor first. It is important that you let your doctor know about any other medication you are taking, or condition you may have, so that they can consider this when prescribing antidepressants for you.

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