Drug Uses
Retin-A -
(Tretinoin) is often used to improve the appearance and texture
of the skin. It produces a mild, superficial peel of the epidermis.
Retin-A - (Tretinoin) has effects on the both the superficial
(epidermis) and the deep (dermis) parts of the skin. The major
benefit is to decrease the effects of sunlight caused aging by
increasing the speed with which the surface cells are replaced.
Tretinoin is a topical form of vitamin A. It helps the skin to
renew itself more quickly and therefore reduces pimple and blackhead
formation, and may improve the appearance and texture of skin.
The Retin-A and Avita brands of tretinoin topical are used to
treat acne. The Renova brand of tretinoin topical is used to reduce
the appearance of fine wrinkles and mottled skin discoloration,
and to make rough facial skin feel smoother. Tretinoin topical
may also be used for purposes other than those listed in this
medication guide.
How Taken
Apply a thin
layer to affected area once a day at bedtime. Use a gauze pad
or cotton swab to apply the liquid. Wash your hands immediately
after use. Using this Retin-A (Retin-A - Tretinoin) more frequently
or in excessive amounts does not improve the results, but may
increase side effects. Avoid applying near the eyes, mouth, or
open cuts since this Retin-A (Retin-A - Tretinoin) can irritate
sensitive skin. Acne may appear to worsen when the Retin-A (Retin-A
- Tretinoin) is first used; continue therapy. It may take three
to six weeks before the full benefits of this Retin-A (Retin-A
- Tretinoin) are seen. Use mild soap when washing your face. Do
not wash face excessively. Abrasive soaps, cleansers, medicated
creams or lotions can increase skin irritation. Consult your doctor
or pharmacist about their use. Use other acne preparations with
caution while using this Retin-A (Retin-A - Tretinoin).
How should
I use Generic Retin-A?
Use Retin-A
exactly as directed by your doctor. If you do not understand these
instructions, ask your pharmacist, nurse, or doctor to explain
them to you. Wash your hands before and after applying this medication.
Retin-A is usually applied once daily at bedtime. Follow your
doctor's instructions. Clean and pat dry the area of skin where
you will apply Retin-A. Applying Retin-A to wet skin may cause
skin irritation. If you are using Renova, wait approximately 20
to 30 minutes after washing your face before applying the medication.
Apply a light covering of the cream, gel, or solution to the area.
Do not wash the treated area for at least 1 hours after applying
Retin-A. Avoid the use of any topical products on the treated
area for at least 1 hour following application of this medication.
Do not apply Retin-A to eyes, ears, nostrils, mouth, angles of
your nose, mucous membranes, open sores, or irritated skin. If
you get medication in any of these areas, rinse it off with water.
Application of an excessive amount of the tretinoin gel may result
in "pilling" of the medication. This does not reduce
the effectiveness of the medication, but if pilling occurs, you
should use less medication with the next application. Retin-A
should be used as part of a comprehensive skin care and sunlight
avoidance program that includes the use of effective sunscreens
(minimum SPF of 15) and protective clothing. Do not stop using
Retin-A if you do not see improvement in your condition immediately.
Treatment with Retin-A may be necessary for weeks or months before
improvement is seen. If you are using Retin-A to treat acne, a
temporary worsening of acne may occur at the start of therapy.
Warnings/Precautions
This Retin-A
(Retin-A - Tretinoin) can increase sensitivity to sunlight, wind
and cold. Avoid prolonged exposure to the sun and sunlamps. Wear
protective clothing and use an effective sunscreen. This Retin-A
(Retin-A - Tretinoin) should be used during pregnancy only if
clearly needed. It is not known if Retin-A - (Tretinoin) appears
in breast milk. Consult your doctor before breast-feeding.
Missed Dose
If you miss
a dose, use it as soon as remembered; do not use if it is almost
time for the next dose, skip the missed dose and resume your usual
dosing schedule. Do not "double-up" the dose to catch
up.
Possible
Side Effects
Due to the
possibility of irritation, it is advisable to begin treatment
on a small area of skin. Exposure to the sun or to ultraviolet
rays causes additional irritation. During treatment, such exposure
should be avoided as much as possible or a sun block should be
used. During the first weeks of treatment there may be an apparent
worsening of the problem. Such a reaction is perfectly normal
because small cysts deep within the skin are being eliminated
at an accelerated rate. This Retin-A (Retin-A - Tretinoin) can
increase sensitivity wind and cold. Avoid prolonged exposure to
the sun and sunlamps. Wear protective clothing and use an effective
sunscreen. If any ingredient should cause hypersensitivity, discontinue
use.
Storage
Store at room
temperature away from sunlight. Keep this and all Retin-A (Retin-A
- Tretinoin)s out of the reach of children.
Overdose
Applying Retin-A
- (Tretinoin) excessively will not produce faster or better results,
and marked redness, peeling, or discomfort could occur. Over dosage
with other retinoid has been associated with transient headache,
facial flushing, celosias, abdominal pain, dizziness and ataxia.
More Information
If you have
been previously treated with keratolytic preparations or exfoliants,
you should wait until any skin rash clears up before beginning
even low strength treatment. Studies of the effect of this product
on pregnant women are incomplete. For this reason, it should only
be applied when absolutely necessary and always under a doctor's
supervision. The effectiveness of Retin-A - (Tretinoin) is almost
always accompanied by skin irritation. In the treatment of acne,
this phenomenon is directly related to the effectiveness of the
product and disappears once applications are more spaced out.
Cosmetics may be used, but clean skin thoroughly before applying
the Retin-A (Retin-A - Tretinoin).
Disclaimer
This drug
information is for your information purposes only, it is not intended
that this information covers all uses, directions, drug interactions,
precautions, or adverse effects of your Retin-A (Retin-A - Tretinoin).
This is only general information, and should not be relied on
for any purpose. It should not be construed as containing specific
instructions for any particular patient. We disclaim all responsibility
for the accuracy and reliability of this information, and/or any
consequences arising from the use of this information, including
damage or adverse consequences to persons or property, however
such damages or consequences arise. No warranty, either expressed
or implied, is made in regards to this information.
What other
drugs will affect Generic Retin-A?
Do not use
Retin-A without first talking to your doctor if you are taking
any of the following medicines: a thiazide diuretic such as hydrochlorothiazide
(HCTZ, HydroDiuril, Esidrix, Microzide, Oretic), chlorothiazide
(Diuril), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol),
metolazone (Mykrox, Zaroxolyn), and others; a tetracycline antibiotic
such as tetracycline (Sumycin, Panmycin, Robitet, others), minocycline
(Dynacin, Minocin, Vectrin), doxycycline (Doryx, Monodox, Vibramycin,
Vibra-Tabs), demeclocycline (Declomycin), and others; a fluoroquinolone
antibiotic such as lomefloxacin (Maxaquin), sparfloxacin (Zagam),
ciprofloxacin (Cipro), ofloxacin (Floxin), and others; a sulfonamide
antibiotic such as sulfamethoxazole (Gantanol), sulfisoxazole
(Gantrisin), sulfamethoxazole-trimethoprim (Bactrim, Septra, Cotrim),
and others; or a phenothiazine such as chlorpromazine (Thorazine),
prochlorperazine (Compazine), fluphenazine (Permitil, Prolixin),
promethazine (Phenergan, Promethegan), perphenazine (Trilafon),
and others. The medications listed above may increase the sensitivity
of your skin to UV rays from sunlight or artificial light (e.g.,
sunlamps). Generally, Retin-A should not be used with any of the
medicines listed above. Do not use products containing benzoyl
peroxide, sulfur, resorcinol, or salicylic acid during treatment
with Retin-A unless otherwise directed by your doctor. The combination
could lead to severe skin irritation. Avoid as much as possible
products that can increase skin irritation such as other skin
medicines (unless prescribed by your doctor); medicated or abrasive
(rough) soaps or skin cleansers; permanent wave solutions.
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