What is Alendronate
Sodium?
-
Alendronate
sodium is the generic name for Fosamax (brand name). Fosamax
is chemically known as a bisphosphonate medication. It is
not a hormone. Fosamax works only on the bone and does not
affect the heart, breast, uterus or other parts of the body.
Alendronate sodium (Fosamax) is taken for the prevention or
treatment of osteoporosis in postmenopausal women and men.
In addition, Fosamax is approved for the treatment of women
and men with osteoporosis resulting from the long-term use
of steroid medications such as prednisone or cortisone. Alendronate
sodium (Fosamax) is FDA-approved for the prevention or treatment
of osteoporosis in postmenopausal women and men. In addition,
Fosamax is approved for the treatment of women and men with
osteoporosis resulting from the long-term use of steroid medications
such as prednisone or cortisone.
Drug Uses
Fosamax -
(Alendronate) is indicated for treatment and prevention of osteoporosis
in postmenopausal women. For the treatment of osteoporosis, Fosamax
- (Alendronate) increases bone mass and reduces the incidence
of fractures, including those of the hip and spine. It is also
indicated for the prevention of osteoporosis, treatment to increase
bone mass in men with osteoporosis, treatment of glucocorticoid.
It is used to treat induced osteoporosis in men and women receiving
glucocorticoids in a daily dosage equivalent to 7.5 mg or greater
of prednisone and who have low bone mineral density, treatment
of Paget's disease of bone in men and women.
How Taken
Fosamax -
(Alendronate) comes as a tablet to take by mouth. It should be
taken once a day in the morning on an empty stomach. Fosamax -
(Alendronate) should be taken with a full glass (6-8 ounces) of
plain water. Wait at least 30 minutes after taking Fosamax - (Alendronate)
before you eat, drink, or take other medications. Do not take
Fosamax - (Alendronate) with mineral water, coffee, orange juice,
milk, or other dairy products. Do not suck or chew the tablet;
swallow the tablet whole. Do not lie down for at least 30 minutes
after taking Fosamax - (Alendronate). Standing or sitting upright
helps you get the full dose and decreases heartburn or the risk
of injury to your esophagus. Fosamax/Alendronate comes as a tablet
to take by mouth. Fosamax/Alendronate should be taken once a day
in the morning on an empty stomach. Fosamax/Alendronate should
be taken with a full glass (6-8 ounces) of plain water. Wait at
least 30 minutes after taking alendronate before you eat, drink,
or take other medications. Do not take Fosamax/alendronate with
mineral water, coffee, orange juice, milk, or other dairy products.
Do not suck or chew the Fosamax/Alendronate tablet; swallow the
Fosamax tablet whole. Do not lie down for at least 30 minutes
after taking Fosamax/alendronate. Standing or sitting upright
helps you get the full dose and decreases heartburn or the risk
of injury to your esophagus. Follow the Fosamax directions on
your Fosamax prescription label carefully, and ask your doctor
or pharmacist to explain any part you do not understand. Take
Fosamax/alendronate exactly as directed. Do not take more or less
of Fosamax or take Fosamax more often than prescribed by your
doctor. Do not stop taking Fosamax/alendronate without talking
to your doctor.
Warnings/Precautions
Before taking
Fosamax - (Alendronate), tell your doctor if you have a problem
swallowing, such as a narrowing of the esophagus; have esophageal
ulcers or an esophageal disease; have a condition that causes
low levels of calcium in the body; have kidney disease; have stomach
ulcers or other stomach or digestive problems; or are unable to
stand or sit upright for at least 30 minutes. You may not be able
to take Fosamax - (Alendronate), or you may require a dosage adjustment
or special monitoring during treatment if you have any of the
conditions listed above. Fosamax - (Alendronate) is in the FDA
pregnancy category C. This means that it is not known whether
Fosamax - (Alendronate) will be harmful to an unborn baby. Do
not take Fosamax - (Alendronate) without first talking to your
doctor if you are pregnant or could become pregnant during treatment.
It is not known whether Fosamax - (Alendronate) passes into breast
milk. Do not take Fosamax - (Alendronate) without first talking
to your doctor if you are breast-feeding a baby.
Missed Dose
If you take
Fosamax - (Alendronate) every day and you miss a dose, skip that
dose and take the next regularly scheduled dose the following
day. Missing one dose will not affect your treatment. Do not take
two tablets at the same time. If you take a Fosamax - (Alendronate)
once a week and you miss a dose, take the missed dose on the morning
after you remember. Do not take two tablets on the same day. Return
to taking one tablet once a week, as originally scheduled on your
chosen day.
Possible
Side Effects
Stop taking
Fosamax - (Alendronate) if you experience any of the following
serious side effects: an allergic reaction (difficulty breathing;
closing of the throat; swelling of the lips, tongue, or face;
or hives); Seek emergency or talk to your doctor if you have difficulty
or pain when swallowing; chest pain; pain or burning under the
ribs or in the back; or new or worsening heartburn. Other, less
serious side effects may be more likely to occur. Continue to
take Fosamax - (Alendronate) and talk to your doctor if you experience
abdominal discomfort; stomach upset, nausea, vomiting, diarrhea,
or constipation; headache; muscle, bone, or joint soreness or
aches; eye pain; a rash; or an altered sense of taste. Side effects
other than those listed here may also occur. Talk to your doctor
about any side effect that seems unusual or that is especially
bothersome.
Storage
Store in a
well-closed container at room temperature, 15-30°C (59-86°F).
Overdose
Hypocalcemia,
hypophosphatemia, and upper gastrointestinal adverse events, such
as upset stomach, heartburn, esophagitis, gastritis, or ulcer,
may result from oral over dosage. If you do think that an overdose
has occurred, call an emergency room or poison control center.
More Information
Follow you
doctor's recommendations about drinking alcohol and smoking. These
activities are related to decreased bone density. Antacids and
other medicines taken by mouth may decrease the effects of Fosamax
- (Alendronate). Do not take any other medicines within 30 minutes
after a dose of Fosamax - (Alendronate). Talk to your doctor before
taking any other medicines during treatment with Fosamax - (Alendronate).
Disclaimer
This drug
information is for your information purposes only, it is not intended
that this information covers all uses, directions, drug interactions,
precautions, or adverse effects of your medication. This is only
general information, and should not be relied on for any purpose.
It should not be construed as containing specific instructions
for any particular patient. We disclaim all responsibility for
the accuracy and reliability of this information, and/or any consequences
arising from the use of this information, including damage or
adverse consequences to persons or property, however such damages
or consequences arise. No warranty, either expressed or implied,
is made in regards to this information.
What drug(s)
may interact with this medicine?
It is important
that you get enough calcium and vitamin D while you are taking
Fosamax/alendronate. Your doctor may prescribe supplements if
your dietary intake is not sufficient. Remember that Fosamax/alendronate
should be taken with at least 6-8 ounces of water. Food, drinks,
and other drugs (including vitamins, calcium, and vitamin D) should
not be taken for at least 30 minutes after taking Fosamax/alendronate.
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