Fludrocortisone - Generic Florinef is used for:

Treating adrenocortical insufficiency in Addison disease and for treating salt-losing adrenogenital syndrome.

Fludrocortisone - Generic Florinef is a corticosteroid. It works by causing the kidneys to retain sodium and acting as a replacement for cortisone when the body does not produce enough.

Do NOT use Fludrocortisone - Generic Florinef if:

• you are allergic to any ingredient in Fludrocortisone - Generic Florinef

• you have a systemic fungal infection

• you are scheduled to have a smallpox vaccination

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fludrocortisone - Generic Florinef :

Some medical conditions may interact with Fludrocortisone - Generic Florinef. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding

• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

• if you have allergies to medicines, foods, or other substances

• if you are scheduled for a vaccination with a live virus vaccine (eg, smallpox)

• if you have a history of an underactive thyroid, liver or kidney problems, heart problems or heart attack, bleeding problems, diabetes, high blood pressure, inflammation of the esophagus, stomach problems (eg, ulcers), bowel blockage or other bowel problems (eg, ulcerative colitis), recent bowel surgery, myasthenia gravis, or mental or mood problems (eg, depression)

• if you have measles, chickenpox, herpes infection of the eye, or any other type of bacterial, fungal, parasitic, or viral infection

• if you have recently had tuberculosis (TB) or have had a positive skin test for TB

Some MEDICINES MAY INTERACT with Fludrocortisone - Generic Florinef. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anabolic steroids (eg, oxymetholone) or aprepitant because side effects of Fludrocortisone - Generic Florinef may be increased

• Barbiturates (eg, phenobarbital), carbamazepine, estrogens, hydantoins (eg, phenytoin), or rifampin because the effectiveness of Fludrocortisone - Generic Florinef may be decreased

• Amphotericin B, azole antifungals (eg, ketoconazole), clarithromycin, digoxin, loop diuretics (eg, furosemide), steroidal contraceptives (eg, desogestrel), thiazide diuretics (eg, hydrochlorothiazide), or troleandomycin because side effects, such as weakness, confusion, muscle aches, irregular heartbeat, joint pain, or low blood sugar, may occur

• Methotrexate or ritodrine because the actions and side effects of these medicines may be increased

• Hydantoins (eg, phenytoin), live vaccines, or smallpox vaccine because the effectiveness of these medicines may be decreased

• Anticoagulants (eg, warfarin) or aspirin because the actions and side effects of these medicines may be increased or decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fludrocortisone - Generic Florinef may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fludrocortisone - Generic Florinef :

Use Fludrocortisone - Generic Florinef as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Fludrocortisone - Generic Florinef may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

• If Fludrocortisone - Generic Florinef needs to be stopped (or if a different medicine is added to therapy) by your doctor, this will be done gradually. The risk of side effects may be increased if Fludrocortisone - Generic Florinef is suddenly stopped.

• If you miss a dose of Fludrocortisone - Generic Florinef , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fludrocortisone - Generic Florinef.

Important safety information:

• Fludrocortisone - Generic Florinef may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Fludrocortisone - Generic Florinef. Using Fludrocortisone - Generic Florinef alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.

• Fludrocortisone - Generic Florinef may lower your body's ability to fight infection, especially if taken over a longer period of time. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rash, or chills.

• If you have not had chickenpox or measles, avoid contact with anyone who has any of these diseases. If you are exposed to anyone with chickenpox or measles, contact your doctor right away.

• Carry an identification card at all times that says you are taking Fludrocortisone - Generic Florinef.

• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Fludrocortisone - Generic Florinef.

• Long-term use may cause cataracts, glaucoma, and eye infections. Contact your doctor right away if you develop any unusual changes in your vision.

• Fludrocortisone - Generic Florinef may cause an increase in blood pressure, salt and water retention, and calcium and potassium loss. Talk with your doctor to see if you need to decrease the amount of salt in your diet or take a calcium or vitamin D supplement.

• Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Fludrocortisone - Generic Florinef. Vaccinations may be less effective.

• Diabetes patients - Fludrocortisone - Generic Florinef may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.

• LAB TESTS, including blood electrolytes, blood calcium levels, blood pressure, and vision tests may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

• Caution is advised when using Fludrocortisone - Generic Florinef in CHILDREN because they may be more sensitive to its effects.

• Corticosteroids may affect the growth rate in CHILDREN and adolescents in some instances. Your child's growth may need to be checked regularly while using Fludrocortisone - Generic Florinef.

• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Fludrocortisone - Generic Florinef , discuss with your doctor the benefits and risks of using Fludrocortisone - Generic Florinef during pregnancy. Fludrocortisone - Generic Florinef is excreted in breast milk. If you are or will be breast-feeding while you are using Fludrocortisone - Generic Florinef , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Fludrocortisone - Generic Florinef :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Difficulty sleeping; dizziness or lightheadedness; headache; increased appetite; increased sweating; indigestion; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in menstrual periods; chest pain; eye pain or increased pressure in the eye; fever, chills, or sore throat; joint or bone pain; mood or mental changes (eg, depression); muscle pain or weakness; seizures; severe or persistent headache; severe or persistent nausea or vomiting; stomach pain or bloating; swelling of feet or legs; trouble sleeping; unusual weight gain or loss; vision changes; vomiting material that looks like coffee grounds.

What is the shelf life of the pills?

• The expiry date is mentioned on each blister. It is different for different batches. The shelf life is 2 years from the date of manufacture and would differ from batch to batch depending on when they were manufactured.

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